Ultraweak Sugar-Sugar Interactions for Transient Cell Adhesion

Ultraweak sugar-sugar interactions for transient cell adhesion.

Carbohydrate-carbohydrate interactions are rarely considered in biologically relevant situations such as cell recognition and adhesion. One Ca(2+)-mediated homotypic interaction between two Lewis(x) determinants (Le(x)) has been proposed to drive cell adhesion in murine embryogenesis. Here, we confirm the existence of this specific interaction by reporting the first direct quantitative measurem...

Sugar and sugar products.

Emphasis over the past year has been on editorial effort to bring Chapter 44, Sugar and Sugar Products of the Official Methods of Analysis of AOAC INTERNATIONAL (OMA) to the high standards set for the 17th Edition of the compendium. In addition, 2 method studies were reported and subjected to peer review, respectively, dealing with detection of adulteration of maple syrup by beet or cane sugar ...

Smart Sugar? The Sugar Conspiracy

Sugar

By 1961 the situation had become reversed. The fibre consumption of the highest income groups relative to that of the lowest increased steadily during this period. When compared to the lowest two social classes the highest two with the higher overall fibre intake emerged with a lower incidence ofCHD over the twenty years.73 Finally, in a prospective secondary prevention study, Daan Kromhout and...

Update on Nucleotide Sugar Synthesis UDP-Sugar Pyrophosphorylase: A New Old Mechanism for Sugar Activation

Simple sugars (e.g. Glc, Gal) are the building blocks of disaccharides (e.g. Suc) and polysaccharides (e.g. cellulose, hemicellulose). To produce disaccharides and polysaccharides, a given simple sugar needs to be “activated.” This activation involves the addition of a nucleoside-diphosphate group to a sugar, resulting in the formation of a nucleotide sugar. Such an activated sugar can then be ...